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Estimation of tumor heterogeneity using CGH array data

BACKGROUND: Array-based comparative genomic hybridization (CGH) is a commonly-used approach to detect DNA copy number variation in whole genome-wide screens. Several statistical methods have been proposed to define genomic segments with different copy numbers in cancer tumors. However, most tumors a...

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Detalles Bibliográficos
Autores principales: Wang, Kai, Li, Jian, Li, Shengting, Bolund, Lars, Wiuf, Carsten
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640360/
https://www.ncbi.nlm.nih.gov/pubmed/19134174
http://dx.doi.org/10.1186/1471-2105-10-12