Transcriptome analysis of murine thymocytes reveals age-associated changes in thymic gene expression

The decline in adaptive immunity, naïve T-cell output and a contraction in the peripheral T cell receptor (TCR) repertoire with age are largely attributable to thymic involution and the loss of critical cytokines and hormones within the thymic microenvironment. To assess the molecular changes associ...

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Detalles Bibliográficos
Autores principales: Lustig, Ana, Carter, Arnell, Bertak, Dorothy, Enika, Divya, Vandanmagsar, Bolormaa, Wood, William, Becker, Kevin G., Weeraratna, Ashani T., Taub, Dennis D.
Formato: Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2009
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640475/
https://www.ncbi.nlm.nih.gov/pubmed/19214242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640475/
https://www.ncbi.nlm.nih.gov/pubmed/19214242

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