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Targeted Inactivation of p12(Cdk2ap1), CDK2 Associating Protein 1, Leads to Early Embryonic Lethality
Targeted disruption of murine Cdk2ap1, an inhibitor of CDK2 function and hence G1/S transition, results in the embryonic lethality with a high penetration rate. Detailed timed pregnancy analysis of embryos showed that the lethality occurred between embryonic day 3.5 pc and 5.5 pc, a period of implan...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2641017/ https://www.ncbi.nlm.nih.gov/pubmed/19229340 http://dx.doi.org/10.1371/journal.pone.0004518 |