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ABIN-1 is a Ubiquitin Sensor that Restricts Cell Death and Sustains Embryonic Development

Proteins that directly regulate TNFR signaling play critical roles in regulating cellular activation and survival. A20 Binding and Inhibitor of NFkB (ABIN-1) is a novel protein that is thought to inhibit NFkB signaling (1, 2). Here we show that mice deficient for ABIN-1 die during embryogenesis with...

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Detalles Bibliográficos
Autores principales: Oshima, Shigeru, Turer, Emre E., Callahan, Joseph A., Chai, Sophia, Advincula, Rommel, Barrera, Julio, Shifrin, Nataliya, Lee, Bettina, Yen, Benjamin, Woo, Tammy, Malynn, Barbara A., Ma, Averil
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642523/
https://www.ncbi.nlm.nih.gov/pubmed/19060883
http://dx.doi.org/10.1038/nature07575