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PERK-dependent regulation of IAP translation during ER stress

Exposure of cells to Endoplasmic Reticulum (ER) stress leads to activation of phosphatidylinositol 3-kinase (PI3K)–Akt signaling pathway and transcriptional induction of the inhibitor of apoptosis family of proteins. One of the proximal effectors of the ER stress response, the PKR-like ER kinase (PE...

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Detalles Bibliográficos
Autores principales: Hamanaka, Robert B., Bobrovnikova-Marjon, Ekaterina, Ji, Xinjun, Liebhaber, Stephen A., Diehl, J. Alan
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642534/
https://www.ncbi.nlm.nih.gov/pubmed/19029953
http://dx.doi.org/10.1038/onc.2008.428