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PERK-dependent regulation of IAP translation during ER stress
Exposure of cells to Endoplasmic Reticulum (ER) stress leads to activation of phosphatidylinositol 3-kinase (PI3K)–Akt signaling pathway and transcriptional induction of the inhibitor of apoptosis family of proteins. One of the proximal effectors of the ER stress response, the PKR-like ER kinase (PE...
Autores principales: | Hamanaka, Robert B., Bobrovnikova-Marjon, Ekaterina, Ji, Xinjun, Liebhaber, Stephen A., Diehl, J. Alan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642534/ https://www.ncbi.nlm.nih.gov/pubmed/19029953 http://dx.doi.org/10.1038/onc.2008.428 |
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