SAFEGUI: resampling-based tests of categorical significance in gene expression data made easy

Summary: A large number of websites and applications perform significance testing for gene categories/pathways in microarray data. Many of these packages fail to account for expression correlation between transcripts, with a resultant inflation in Type I error. Array permutation and other resampling...

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Detalles Bibliográficos
Autores principales: Gatti, Daniel M., Sypa, Myroslav, Rusyn, Ivan, Wright, Fred A., Barry, William T.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642635/
https://www.ncbi.nlm.nih.gov/pubmed/19098030
http://dx.doi.org/10.1093/bioinformatics/btn655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642635/
https://www.ncbi.nlm.nih.gov/pubmed/19098030
http://dx.doi.org/10.1093/bioinformatics/btn655

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