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SAFEGUI: resampling-based tests of categorical significance in gene expression data made easy
Summary: A large number of websites and applications perform significance testing for gene categories/pathways in microarray data. Many of these packages fail to account for expression correlation between transcripts, with a resultant inflation in Type I error. Array permutation and other resampling...
Autores principales: | Gatti, Daniel M., Sypa, Myroslav, Rusyn, Ivan, Wright, Fred A., Barry, William T. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642635/ https://www.ncbi.nlm.nih.gov/pubmed/19098030 http://dx.doi.org/10.1093/bioinformatics/btn655 |
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