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Differential impact of l-arginine deprivation on the activation and effector functions of T cells and macrophages

The metabolism of the amino acid l-arginine is emerging as a crucial mechanism for the regulation of immune responses. Here, we characterized the impact of l-arginine deprivation on T cell and macrophage (MΦ) effector functions: We show that whereas l-arginine is required unconditionally for T cell...

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Detalles Bibliográficos
Autores principales: Choi, B.-S., Martinez-Falero, I. Clara, Corset, C., Munder, M., Modolell, M., Müller, I., Kropf, P.
Formato: Texto
Lenguaje:English
Publicado: The Society for Leukocyte Biology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642643/
https://www.ncbi.nlm.nih.gov/pubmed/19008294
http://dx.doi.org/10.1189/jlb.0508310