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Evaluation of intracellular signalling pathways in response to insulin-like growth factor I in apoptotic-resistant activated human hepatic stellate cells

BACKGROUND: Human hepatic stellate cells have been shown to be resistant to apoptotic stimuli. This is likely dependent on the activation of anti-apoptotic pathways upon transition of these cells to myofibroblast-like cells. In particular, previous studies have demonstrated an increased expression o...

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Detalles Bibliográficos
Autores principales: Gentilini, Alessandra, Lottini, Benedetta, Brogi, Marco, Caligiuri, Alessandra, Cosmi, Lorenzo, Marra, Fabio, Pinzani, Massimo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642760/
https://www.ncbi.nlm.nih.gov/pubmed/19183465
http://dx.doi.org/10.1186/1755-1536-2-1