Issues associated with assessing nuclear localization of N-terminally unphosphorylated β-catenin with monoclonal antibody 8E7

BACKGROUND: β-catenin is a dual function adhesion/transcriptional co-activator protein, and both functions are critical for normal tissue homeostasis. Since the transcriptional functions of β-catenin are more often implicated in various disease processes, there is much interest in the development an...

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Detalles Bibliográficos
Autores principales: Maher, Meghan T, Flozak, Annette S, Hartsell, Alyssa M, Russell, Susan, Beri, Rohinee, Peled, Ofra N, Gottardi, Cara J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642777/
https://www.ncbi.nlm.nih.gov/pubmed/19187541
http://dx.doi.org/10.1186/1745-6150-4-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642777/
https://www.ncbi.nlm.nih.gov/pubmed/19187541
http://dx.doi.org/10.1186/1745-6150-4-5

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