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Mismatch oligonucleotides in human and yeast: guidelines for probe design on tiling microarrays

BACKGROUND: Mismatched oligonucleotides are widely used on microarrays to differentiate specific from nonspecific hybridization. While many experiments rely on such oligos, the hybridization behavior of various degrees of mismatch (MM) structure has not been extensively studied. Here, we present the...

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Detalles Bibliográficos
Autores principales: Seringhaus, Michael, Rozowsky, Joel, Royce, Thomas, Nagalakshmi, Ugrappa, Jee, Justin, Snyder, Michael, Gerstein, Mark
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642824/
https://www.ncbi.nlm.nih.gov/pubmed/19117516
http://dx.doi.org/10.1186/1471-2164-9-635