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Mismatch oligonucleotides in human and yeast: guidelines for probe design on tiling microarrays
BACKGROUND: Mismatched oligonucleotides are widely used on microarrays to differentiate specific from nonspecific hybridization. While many experiments rely on such oligos, the hybridization behavior of various degrees of mismatch (MM) structure has not been extensively studied. Here, we present the...
Autores principales: | Seringhaus, Michael, Rozowsky, Joel, Royce, Thomas, Nagalakshmi, Ugrappa, Jee, Justin, Snyder, Michael, Gerstein, Mark |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642824/ https://www.ncbi.nlm.nih.gov/pubmed/19117516 http://dx.doi.org/10.1186/1471-2164-9-635 |
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