Over half of breakpoints in gene pairs involved in cancer-specific recurrent translocations are mapped to human chromosomal fragile sites

BACKGROUND: Gene rearrangements such as chromosomal translocations have been shown to contribute to cancer development. Human chromosomal fragile sites are regions of the genome especially prone to breakage, and have been implicated in various chromosome abnormalities found in cancer. However, there...

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Detalles Bibliográficos
Autores principales: Burrow, Allison A, Williams, Laura E, Pierce, Levi CT, Wang, Yuh-Hwa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642838/
https://www.ncbi.nlm.nih.gov/pubmed/19183484
http://dx.doi.org/10.1186/1471-2164-10-59

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642838/
https://www.ncbi.nlm.nih.gov/pubmed/19183484
http://dx.doi.org/10.1186/1471-2164-10-59

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