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Cytoplasmic CXCR4 expression in breast cancer: induction by nitric oxide and correlation with lymph node metastasis and poor prognosis

BACKGROUND: Lymph nodes constitute the first site of metastasis for most malignancies, and the extent of lymph node involvement is a major criterion for evaluating patient prognosis. The CXC chemokine receptor 4 (CXCR4) has been shown to play an important role in lymph node metastasis. Nitric oxide...

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Detalles Bibliográficos
Autores principales: Yasuoka, Hironao, Tsujimoto, Masahiko, Yoshidome, Katsuhide, Nakahara, Masaaki, Kodama, Rieko, Sanke, Tokio, Nakamura, Yasushi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642845/
https://www.ncbi.nlm.nih.gov/pubmed/19025611
http://dx.doi.org/10.1186/1471-2407-8-340