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Proteomic and phototoxic characterization of melanolipofuscin: Correlation to disease and model for its origin

PURPOSE: Melanolipofuscin (MLF) is a complex granule, exhibiting properties of both melanosomes and lipofuscin (LF) granules, which accumulates in retinal pigment epithelial (RPE) cells and may contribute to the etiology of age-related macular degeneration (AMD). MLF accumulation has been reported b...

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Detalles Bibliográficos
Autores principales: Warburton, Sarah, Davis, Wayne E., Southwick, Katie, Xin, Huijun, Woolley, Adam T., Burton, Gregory F., Thulin, Craig D.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642915/
https://www.ncbi.nlm.nih.gov/pubmed/17392682