Elevated insulin signaling disrupts the growth and differentiation pattern of the mouse lens

PURPOSE: Insulin and insulin-like growth factors (IGFs) are putative regulators of cell proliferation and differentiation during lens development. Transgenic mice that overexpress IGF-1 in the lens have been previously described. To further understand the ocular functions of this growth factor famil...

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Detalles Bibliográficos
Autores principales: Xie, Leike, Chen, Huiyi, Overbeek, Paul A., Reneker, Lixing W.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642934/
https://www.ncbi.nlm.nih.gov/pubmed/17417601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642934/
https://www.ncbi.nlm.nih.gov/pubmed/17417601

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