Enhancement of the Seed-Target Recognition Step in RNA Silencing by a PIWI/MID Domain Protein

Target recognition in RNA silencing is governed by the “seed sequence” of a guide RNA strand associated with the PIWI/MID domain of an Argonaute protein in RISC. Using a reconstituted in vitro target recognition system, we show that a model PIWI/MID domain protein confers position-dependent tighteni...

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Detalles Bibliográficos
Autores principales: Parker, James S., Parizotto, Eneida A., Wang, Muhan, Roe, S. Mark, Barford, David
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642989/
https://www.ncbi.nlm.nih.gov/pubmed/19187762
http://dx.doi.org/10.1016/j.molcel.2008.12.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642989/
https://www.ncbi.nlm.nih.gov/pubmed/19187762
http://dx.doi.org/10.1016/j.molcel.2008.12.012

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