The Glycogen-Binding Domain on the AMPK β Subunit Allows the Kinase to Act as a Glycogen Sensor

AMPK β subunits contain a conserved domain that causes association with glycogen. Although glycogen availability is known to affect AMPK regulation in vivo, the molecular mechanism for this has not been clear. We now show that AMPK is inhibited by glycogen, particularly preparations with high branch...

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Detalles Bibliográficos
Autores principales: McBride, Andrew, Ghilagaber, Stephanos, Nikolaev, Andrei, Hardie, D. Grahame
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642990/
https://www.ncbi.nlm.nih.gov/pubmed/19117544
http://dx.doi.org/10.1016/j.cmet.2008.11.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642990/
https://www.ncbi.nlm.nih.gov/pubmed/19117544
http://dx.doi.org/10.1016/j.cmet.2008.11.008

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