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Genetic Subtype Differences in Neural Circuitry of Food Motivation in Prader-Willi Syndrome

BACKGROUND: Differences in behavioral phenotypes between the two most common subtypes of Prader-Willi syndrome (PWS) [chromosome 15q deletions and maternal uniparental disomy 15 (UPD)] indicate that distinct neural networks may be affected. Though both subtypes display hyperphagia, the deletion subg...

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Detalles Bibliográficos
Autores principales: Holsen, Laura M., Zarcone, Jennifer R., Chambers, Rebecca, Butler, Merlin G., Bittel, Douglas C., Brooks, William M., Thompson, Travis I., Savage, Cary R.
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643328/
https://www.ncbi.nlm.nih.gov/pubmed/19048015
http://dx.doi.org/10.1038/ijo.2008.255