Computer Aided Identification of Small Molecules Disrupting uPAR/α5β1- Integrin Interaction: A New Paradigm for Metastasis Prevention

BACKGROUND: Disseminated dormant cancer cells can resume growth and eventually form overt metastases, but the underlying molecular mechanism responsible for this change remains obscure. We previously established that cell surface interaction between urokinase receptor (uPAR) and α5β1-integrin initia...

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Detalles Bibliográficos
Autores principales: Chaurasia, Pratima, Mezei, Mihaly, Zhou, Ming-Ming, Ossowski, Liliana
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643475/
https://www.ncbi.nlm.nih.gov/pubmed/19242538
http://dx.doi.org/10.1371/journal.pone.0004617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643475/
https://www.ncbi.nlm.nih.gov/pubmed/19242538
http://dx.doi.org/10.1371/journal.pone.0004617

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