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L-DOPA Neurotoxicity Is Mediated by Up-Regulation of DMT1−IRE Expression

BACKGROUND: The mechanisms underlying neurotoxicity caused by L-DOPA are not yet completely known. Based on recent findings, we speculated that the increased expression of divalent metal transporter 1 without iron-response element (DMT1−IRE) induced by L-DOPA might play a critical role in the develo...

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Detalles Bibliográficos
Autores principales: Du, Fang, Qian, Zhong-ming, Zhu, Li, Wu, Xiao Mei, Yung, Wing-ho, Tsim, Ting-yuk, Ke, Ya
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643485/
https://www.ncbi.nlm.nih.gov/pubmed/19240805
http://dx.doi.org/10.1371/journal.pone.0004593