Cargando…
L-DOPA Neurotoxicity Is Mediated by Up-Regulation of DMT1−IRE Expression
BACKGROUND: The mechanisms underlying neurotoxicity caused by L-DOPA are not yet completely known. Based on recent findings, we speculated that the increased expression of divalent metal transporter 1 without iron-response element (DMT1−IRE) induced by L-DOPA might play a critical role in the develo...
Autores principales: | Du, Fang, Qian, Zhong-ming, Zhu, Li, Wu, Xiao Mei, Yung, Wing-ho, Tsim, Ting-yuk, Ke, Ya |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643485/ https://www.ncbi.nlm.nih.gov/pubmed/19240805 http://dx.doi.org/10.1371/journal.pone.0004593 |
Ejemplares similares
-
Combination Treatment of Icariin and L-DOPA Against 6-OHDA-Lesioned Dopamine Neurotoxicity
por: Lu, Di-Sheng, et al.
Publicado: (2018) -
Corrigendum: Combination Treatment of Icariin and L-DOPA Against 6-OHDA-Lesioned Dopamine Neurotoxicity
por: Lu, Di-Sheng, et al.
Publicado: (2020) -
L-DOPA
por: Hornykiewicz, Oleh
Publicado: (2017) -
IRE-dependent Regulation of Intestinal Dmt1 Prevails During Chronic Dietary Iron Deficiency but is Dispensable in Conditions of Acute Erythropoietic Stress
por: Qatato, Maria, et al.
Publicado: (2022) -
L-Dopa and Behavior
por: Kebabian, John
Publicado: (1974)