Cargando…

Validation and extension of an empirical Bayes method for SNP calling on Affymetrix microarrays

Multiple algorithms have been developed for the purpose of calling single nucleotide polymorphisms (SNPs) from Affymetrix microarrays. We extend and validate the algorithm CRLMM, which incorporates HapMap information within an empirical Bayes framework. We find CRLMM to be more accurate than the Aff...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Shin, Carvalho, Benilton, Cutler, David J, Arking, Dan E, Chakravarti, Aravinda, Irizarry, Rafael A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643934/
https://www.ncbi.nlm.nih.gov/pubmed/18387188
http://dx.doi.org/10.1186/gb-2008-9-4-r63