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Evolutionary potentials: structure specific knowledge-based potentials exploiting the evolutionary record of sequence homologs

We introduce a new type of knowledge-based potentials for protein structure prediction, called 'evolutionary potentials', which are derived using a single experimental protein structure and all three-dimensional models of its homologous sequences. The new potentials have been benchmarked a...

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Detalles Bibliográficos
Autores principales: Panjkovich, Alejandro, Melo, Francisco, Marti-Renom, Marc A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643939/
https://www.ncbi.nlm.nih.gov/pubmed/18397517
http://dx.doi.org/10.1186/gb-2008-9-4-r68