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Natural selection of protein structural and functional properties: a single nucleotide polymorphism perspective

BACKGROUND: The rates of molecular evolution for protein-coding genes depend on the stringency of functional or structural constraints. The Ka/Ks ratio has been commonly used as an indicator of selective constraints and is typically calculated from interspecies alignments. Recent accumulation of sin...

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Detalles Bibliográficos
Autores principales: Liu, Jinfeng, Zhang, Yan, Lei, Xingye, Zhang, Zemin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643940/
https://www.ncbi.nlm.nih.gov/pubmed/18397526
http://dx.doi.org/10.1186/gb-2008-9-4-r69