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Natural selection of protein structural and functional properties: a single nucleotide polymorphism perspective
BACKGROUND: The rates of molecular evolution for protein-coding genes depend on the stringency of functional or structural constraints. The Ka/Ks ratio has been commonly used as an indicator of selective constraints and is typically calculated from interspecies alignments. Recent accumulation of sin...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643940/ https://www.ncbi.nlm.nih.gov/pubmed/18397526 http://dx.doi.org/10.1186/gb-2008-9-4-r69 |