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A model for DNA replication showing how dormant origins safeguard against replication fork failure
Replication origins are ‘licensed' for a single initiation event before entry into S phase; however, many licensed replication origins are not used, but instead remain dormant. The use of these dormant origins helps cells to survive replication stresses that block replication fork movement. Her...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644062/ https://www.ncbi.nlm.nih.gov/pubmed/19218919 http://dx.doi.org/10.1038/embor.2009.5 |