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Input–output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic data
The ErbB signaling pathways, which regulate diverse physiological responses such as cell survival, proliferation and motility, have been subjected to extensive molecular analysis. Nonetheless, it remains poorly understood how different ligands induce different responses and how this is affected by o...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644173/ https://www.ncbi.nlm.nih.gov/pubmed/19156131 http://dx.doi.org/10.1038/msb.2008.74 |