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High Resistance of Plasmodium falciparum to Sulphadoxine/Pyrimethamine in Northern Tanzania and the Emergence of dhps Resistance Mutation at Codon 581

BACKGROUND: Sulphadoxine-pyrimethamine (SP) a widely used treatment for uncomplicated malaria and recommended for intermittent preventive treatment of malaria in pregnancy, is being investigated for intermittent preventive treatment of malaria in infants (IPTi). High levels of drug resistance to SP...

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Detalles Bibliográficos
Autores principales: Gesase, Samwel, Gosling, Roly D., Hashim, Ramadhan, Ord, Rosalynn, Naidoo, Inbarani, Madebe, Rashid, Mosha, Jacklin F., Joho, Angel, Mandia, Victor, Mrema, Hedwiga, Mapunda, Ephraim, Savael, Zacharia, Lemnge, Martha, Mosha, Frank W., Greenwood, Brian, Roper, Cally, Chandramohan, Daniel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644264/
https://www.ncbi.nlm.nih.gov/pubmed/19238219
http://dx.doi.org/10.1371/journal.pone.0004569