AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis

Bacterial pathogens need to scavenge iron from their host for growth and proliferation during infection. They have evolved several strategies to do this, one being the biosynthesis and excretion of small, high-affinity iron chelators known as siderophores. The biosynthesis of siderophores is an impo...

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Detalles Bibliográficos
Autores principales: Schmelz, Stefan, Kadi, Nadia, McMahon, Stephen A., Song, Lijiang, Oves-Costales, Daniel, Oke, Muse, Liu, Huanting, Johnson, Kenneth A., Carter, Lester G., Botting, Catherine H., White, Malcolm F., Challis, Gregory L., Naismith, James H.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644304/
https://www.ncbi.nlm.nih.gov/pubmed/19182782
http://dx.doi.org/10.1038/nchembio.145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644304/
https://www.ncbi.nlm.nih.gov/pubmed/19182782
http://dx.doi.org/10.1038/nchembio.145

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