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PGC-1alpha as modifier of onset age in Huntington disease

Although there is a strong correlation between CAG repeat length and age at onset (AO) of motor symptoms, individual Huntington disease (HD) patients may differ dramatically in onset age and disease manifestations despite similar CAG repeat lengths. This has led to a search for genetic factors that...

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Detalles Bibliográficos
Autores principales: Taherzadeh-Fard, Elahe, Saft, Carsten, Andrich, Jürgen, Wieczorek, Stefan, Arning, Larissa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644307/
https://www.ncbi.nlm.nih.gov/pubmed/19200361
http://dx.doi.org/10.1186/1750-1326-4-10