Biomarkers of Human Exposure to Acrylamide and Relation to Polymorphisms in Metabolizing Genes

Acrylamide (AA) is formed in heat treated carbohydrate rich foods in the so-called Maillard reaction. AA is readily absorbed in the body and converted to glycidamide (GA) by epoxidation by the CYP2E1 (cytochrome P450 2E) enzyme. Both AA and GA may be detoxified through direct conjunction to glutathi...

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Detalles Bibliográficos
Autores principales: Duale, Nur, Bjellaas, Thomas, Alexander, Jan, Becher, Georg, Haugen, Margaretha, Paulsen, Jan Erik, Frandsen, Henrik, Olesen, Pelle Thonning, Brunborg, Gunnar
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Genetic Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644397/
https://www.ncbi.nlm.nih.gov/pubmed/19131562
http://dx.doi.org/10.1093/toxsci/kfn269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644397/
https://www.ncbi.nlm.nih.gov/pubmed/19131562
http://dx.doi.org/10.1093/toxsci/kfn269

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