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Targeting mtor-dependent tumours with specific inhibitors: a model for personalized medicine based on molecular diagnoses

Cancer cells are characterized by aberrant growth arising from deregulated signalling pathways. The mammalian target of rapamycin (mtor) pathway integrates multiple growth signals coming from both intracellular and extracellular cues. In this short review, we summarize what is known about the effica...

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Detalles Bibliográficos
Autores principales: Furic, L., Livingstone, M., Dowling, R.J.O., Sonenberg, N.
Formato: Texto
Lenguaje:English
Publicado: Multimed Inc. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644626/
https://www.ncbi.nlm.nih.gov/pubmed/19229373