Hearing loss in a mouse model of Muenke syndrome

The heterozygous Pro250Arg substitution mutation in fibroblast growth factor receptor 3 (FGFR3), which increases ligand-dependent signalling, is the most common genetic cause of craniosynostosis in humans and defines Muenke syndrome. Since FGF signalling plays dosage-sensitive roles in the different...

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Detalles Bibliográficos
Autores principales: Mansour, Suzanne L., Twigg, Stephen R.F., Freeland, Rowena M., Wall, Steven A., Li, Chaoying, Wilkie, Andrew O.M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644644/
https://www.ncbi.nlm.nih.gov/pubmed/18818193
http://dx.doi.org/10.1093/hmg/ddn311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644644/
https://www.ncbi.nlm.nih.gov/pubmed/18818193
http://dx.doi.org/10.1093/hmg/ddn311

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