The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway

Tuberous sclerosis complex (TSC) is a tumor suppressor gene syndrome in which severe renal cystic disease can occur. Many renal cystic diseases, including autosomal dominant polycystic kidney disease (ADPKD), are associated with absence or dysfunction of the primary cilium. We report here that hamar...

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Detalles Bibliográficos
Autores principales: Hartman, Tiffiney R., Liu, Dongyan, Zilfou, Jack T., Robb, Victoria, Morrison, Tasha, Watnick, Terry, Henske, Elizabeth P.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644647/
https://www.ncbi.nlm.nih.gov/pubmed/18845692
http://dx.doi.org/10.1093/hmg/ddn325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644647/
https://www.ncbi.nlm.nih.gov/pubmed/18845692
http://dx.doi.org/10.1093/hmg/ddn325

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