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Exercise intolerance and systemic manifestations of pulmonary emphysema in a mouse model

BACKGROUND: Systemic effects of chronic obstructive pulmonary disease (COPD) significantly contribute to severity and mortality of the disease. We aimed to develop a COPD/emphysema model exhibiting systemic manifestations of the disease. METHODS: Female NMRI mice were treated 5 times intratracheally...

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Detalles Bibliográficos
Autores principales: Lüthje, Lars, Raupach, Tobias, Michels, Hellmuth, Unsöld, Bernhard, Hasenfuss, Gerd, Kögler, Harald, Andreas, Stefan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644670/
https://www.ncbi.nlm.nih.gov/pubmed/19175913
http://dx.doi.org/10.1186/1465-9921-10-7