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Dictyostelium cells bind a secreted autocrine factor that represses cell proliferation

BACKGROUND: Dictyostelium cells secrete the proteins AprA and CfaD. Cells lacking either AprA or CfaD proliferate faster than wild type, while AprA or CfaD overexpressor cells proliferate slowly, indicating that AprA and CfaD are autocrine factors that repress proliferation. CfaD interacts with AprA...

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Detalles Bibliográficos
Autores principales: Choe, Jonathan M, Bakthavatsalam, Deenadayalan, Phillips, Jonathan E, Gomer, Richard H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644720/
https://www.ncbi.nlm.nih.gov/pubmed/19187549
http://dx.doi.org/10.1186/1471-2091-10-4