Cargando…

Dictyostelium cells bind a secreted autocrine factor that represses cell proliferation

BACKGROUND: Dictyostelium cells secrete the proteins AprA and CfaD. Cells lacking either AprA or CfaD proliferate faster than wild type, while AprA or CfaD overexpressor cells proliferate slowly, indicating that AprA and CfaD are autocrine factors that repress proliferation. CfaD interacts with AprA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Choe, Jonathan M, Bakthavatsalam, Deenadayalan, Phillips, Jonathan E, Gomer, Richard H
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644720/ https://www.ncbi.nlm.nih.gov/pubmed/19187549 http://dx.doi.org/10.1186/1471-2091-10-4

Ejemplares similares

A Dictyostelium chalone uses G proteins to regulate proliferation
por: Bakthavatsalam, Deenadayalan, et al.
Publicado: (2009)

The Putative bZIP Transcripton Factor BzpN Slows Proliferation and Functions in the Regulation of Cell Density by Autocrine Signals in Dictyostelium
por: Phillips, Jonathan E., et al.
Publicado: (2011)

The p21-Activated Kinase (PAK) Family Member PakD Is Required for Chemorepulsion and Proliferation Inhibition by Autocrine Signals in Dictyostelium discoideum
por: Phillips, Jonathan E., et al.
Publicado: (2014)

An Autocrine Proliferation Repressor Regulates Dictyostelium discoideum Proliferation and Chemorepulsion Using the G Protein-Coupled Receptor GrlH
por: Tang, Yu, et al.
Publicado: (2018)

A Dictyostelium Secreted Factor Requires a PTEN-Like Phosphatase to Slow Proliferation and Induce Chemorepulsion
por: Herlihy, Sarah E., et al.
Publicado: (2013)

An Autocrine Negative Feedback Loop Inhibits Dictyostelium discoideum Proliferation through Pathways Including IP3/Ca(2+)
por: Tang, Yu, et al.
Publicado: (2021)

Partial genetic suppression of a loss-of-function mutant of the neuronal ceroid lipofuscinosis-associated protease TPP1 in Dictyostelium discoideum
por: Phillips, Jonathan E., et al.
Publicado: (2015)

Linking Ras to myosin function: RasGEF Q, a Dictyostelium exchange factor for RasB, affects myosin II functions
por: Mondal, Subhanjan, et al.
Publicado: (2008)

The Use of Diffusion Calculations and Monte Carlo Simulations to Understand the Behavior of Cells in Dictyostelium Communities
por: Gomer, Richard H.
Publicado: (2019)

The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles
por: Wilkins, Andrew, et al.
Publicado: (2005)

Glutamate secretion by embryonic stem cells as an autocrine signal to promote proliferation
por: Teng, Lin, et al.
Publicado: (2023)

Dictyostelium discoideum cells retain nutrients when the cells are about to outgrow their food source
por: Rijal, Ramesh, et al.
Publicado: (2022)

Using Dictyostelium to Develop Therapeutics for Acute Respiratory Distress Syndrome
por: Kirolos, Sara A., et al.
Publicado: (2021)

Autocrine Extra-Pancreatic Trypsin 3 Secretion Promotes Cell Proliferation and Survival in Esophageal Adenocarcinoma
por: Han, Song, et al.
Publicado: (2013)

SPARC promotes pancreatic cancer cell proliferation and migration through autocrine secretion into the extracellular milieu
por: Pan, Kehua, et al.
Publicado: (2021)

ATP is an essential autocrine factor for pancreatic β‐cell signaling and insulin secretion
por: Hauke, Sebastian, et al.
Publicado: (2022)

Starvation Induces Extracellular Accumulation of Polyphosphate in Dictyostelium discoideum to Inhibit Macropinocytosis, Phagocytosis, and Exocytosis
por: Rijal, Ramesh, et al.
Publicado: (2023)

The putative G protein–coupled receptor GrlD mediates extracellular polyphosphate sensing in Dictyostelium discoideum
por: Suess, Patrick M., et al.
Publicado: (2019)

Identification of novel proteins in the Dictyostelium discoideum chemorepulsion pathway using REMI
por: Kirolos, Sara A, et al.
Publicado: (2022)

Autocrine Secretion of Interferon γ Negatively Regulates Homing of Immature B Cells
por: Flaishon, Liat, et al.
Publicado: (2000)

Schwann cell proliferation in vitro is under negative autocrine control
Publicado: (1990)

Polyphosphate uses mTOR, pyrophosphate, and Rho GTPase components to potentiate bacterial survival in Dictyostelium
por: Rahman, Ryan J., et al.
Publicado: (2023)

A phosphatidylinositol phosphate kinase inhibits Ras activation and regulates chemorepulsion in Dictyostelium discoideum
por: Kirolos, Sara A., et al.
Publicado: (2023)

Dictyostelium : evolution, cell biology, and the development of multicellularity
por: Kessin, Richard H., 1944-
Publicado: (2001)

Secondary Ion Mass Spectrometry Imaging of Dictyostelium discoideum Aggregation Streams
por: DeBord, John Daniel, et al.
Publicado: (2014)

Integrin and autocrine IGF2 pathways control fasting insulin secretion in β-cells
por: Arous, Caroline, et al.
Publicado: (2021)

Acute Myelogenous Leukemia Cells Secrete Factors that Stimulate Cellular LDL Uptake via Autocrine and Paracrine Mechanisms
por: Bhuiyan, Hasanuzzaman, et al.
Publicado: (2017)

Pycnosomes: Condensed Endosomal Structures Secreted by Dictyostelium Amoebae
por: Sabra, Ayman, et al.
Publicado: (2016)

Expression of Gp78/Autocrine Motility Factor Receptor and Endocytosis of Autocrine Motility Factor in Human Thyroid Cancer Cells
por: Wiseman, Sam M, et al.
Publicado: (2019)

ZEB1-repressed microRNAs inhibit autocrine signaling that promotes vascular mimicry of breast cancer cells
por: Langer, E M, et al.
Publicado: (2018)

Autocrine motility factor receptor promotes the proliferation of human acute monocytic leukemia THP-1 cells
por: WANG, YINGCHAO, et al.
Publicado: (2015)

Transcriptional Repression by a bZIP Protein Regulates Dictyostelium Prespore Differentiation
por: Nuñez-Corcuera, Beatriz, et al.
Publicado: (2012)

Secreted Cyclic Di-GMP Induces Stalk Cell Differentiation in the Eukaryote Dictyostelium discoideum
por: Chen, Zhi-hui, et al.
Publicado: (2015)

Bleb-driven chemotaxis of Dictyostelium cells
por: Zatulovskiy, Evgeny, et al.
Publicado: (2014)

The CLE33 peptide represses phloem differentiation via autocrine and paracrine signaling in Arabidopsis
por: Carbonnel, Samy, et al.
Publicado: (2023)

TNF-α Affects Human Cortical Neural Progenitor Cell Differentiation through the Autocrine Secretion of Leukemia Inhibitory Factor
por: Lan, Xiqian, et al.
Publicado: (2012)

Stimulated Human Mast Cells Secrete Mitochondrial Components That Have Autocrine and Paracrine Inflammatory Actions
por: Zhang, Bodi, et al.
Publicado: (2012)

Oncogenic Ras-Induced Proliferation Requires Autocrine Fibroblast Growth Factor 2 Signaling in Skeletal Muscle Cells
por: Fedorov, Yuri V., et al.
Publicado: (2001)

Calmodulin and Calmodulin Binding Proteins in Dictyostelium: A Primer
por: O’Day, Danton H., et al.
Publicado: (2020)

CXCL5 promotes the proliferation and migration of glioma cells in autocrine- and paracrine-dependent manners
por: Dai, Zhijie, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2k1sdcb7v235d83qhkh3cpbvor