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The SET Complex Acts as a Barrier to Autointegration of HIV-1

Retroviruses and retrotransposons are vulnerable to a suicidal pathway known as autointegration, which occurs when the 3′-ends of the reverse transcript are activated by integrase and then attack sites within the viral DNA. Retroelements have diverse strategies for suppressing autointegration, but h...

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Detalles Bibliográficos
Autores principales: Yan, Nan, Cherepanov, Peter, Daigle, Janet E., Engelman, Alan, Lieberman, Judy
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644782/
https://www.ncbi.nlm.nih.gov/pubmed/19266025
http://dx.doi.org/10.1371/journal.ppat.1000327