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Death and Resurrection of the Human IRGM Gene

Immunity-related GTPases (IRG) play an important role in defense against intracellular pathogens. One member of this gene family in humans, IRGM, has been recently implicated as a risk factor for Crohn's disease. We analyzed the detailed structure of this gene family among primates and showed t...

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Detalles Bibliográficos
Autores principales: Bekpen, Cemalettin, Marques-Bonet, Tomas, Alkan, Can, Antonacci, Francesca, Leogrande, Maria Bruna, Ventura, Mario, Kidd, Jeffrey M., Siswara, Priscillia, Howard, Jonathan C., Eichler, Evan E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644816/
https://www.ncbi.nlm.nih.gov/pubmed/19266026
http://dx.doi.org/10.1371/journal.pgen.1000403