Cargando…

A-RAF Kinase Functions in ARF6 Regulated Endocytic Membrane Traffic

BACKGROUND: RAF kinases direct ERK MAPK signaling to distinct subcellular compartments in response to growth factor stimulation. METHODOLOGY/PRINCIPAL FINDINGS: Of the three mammalian isoforms A-RAF is special in that one of its two lipid binding domains mediates a unique pattern of membrane localiz...

Descripción completa

Detalles Bibliográficos
Autores principales: Nekhoroshkova, Elena, Albert, Stefan, Becker, Matthias, Rapp, Ulf R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645234/
https://www.ncbi.nlm.nih.gov/pubmed/19247477
http://dx.doi.org/10.1371/journal.pone.0004647