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A-RAF Kinase Functions in ARF6 Regulated Endocytic Membrane Traffic
BACKGROUND: RAF kinases direct ERK MAPK signaling to distinct subcellular compartments in response to growth factor stimulation. METHODOLOGY/PRINCIPAL FINDINGS: Of the three mammalian isoforms A-RAF is special in that one of its two lipid binding domains mediates a unique pattern of membrane localiz...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645234/ https://www.ncbi.nlm.nih.gov/pubmed/19247477 http://dx.doi.org/10.1371/journal.pone.0004647 |