Influence of vector design and host cell on the mechanism of recombination and emergence of mutant subpopulations of replicating retroviral vectors

BACKGROUND: The recent advent of murine leukaemia virus (MLV)-based replication-competent retroviral (RCR) vector technology has provided exciting new tools for gene delivery, albeit the advances in vector efficiency which have been realized are also accompanied by a set of fresh challenges. The exp...

Descripción completa

Detalles Bibliográficos
Autores principales: Paar, Matthias, Klein, Dieter, Salmons, Brian, Günzburg, Walter H, Renner, Matthias, Portsmouth, Daniel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645402/
https://www.ncbi.nlm.nih.gov/pubmed/19203366
http://dx.doi.org/10.1186/1471-2199-10-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645402/
https://www.ncbi.nlm.nih.gov/pubmed/19203366
http://dx.doi.org/10.1186/1471-2199-10-8

Ejemplares similares