Upregulation of CRABP1 in human neuroblastoma cells overproducing the Alzheimer-typical Aβ(42 )reduces their differentiation potential

BACKGROUND: Alzheimer's disease (AD) is characterized by neurodegeneration and changes in cellular processes, including neurogenesis. Proteolytic processing of the amyloid precursor protein (APP) plays a central role in AD. Owing to varying APP processing, several β-amyloid peptides (Aβ) are ge...

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Detalles Bibliográficos
Autores principales: Uhrig, Markus, Brechlin, Peter, Jahn, Olaf, Knyazev, Yuri, Weninger, Annette, Busia, Laura, Honarnejad, Kamran, Otto, Markus, Hartmann, Tobias
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645429/
https://www.ncbi.nlm.nih.gov/pubmed/19087254
http://dx.doi.org/10.1186/1741-7015-6-38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645429/
https://www.ncbi.nlm.nih.gov/pubmed/19087254
http://dx.doi.org/10.1186/1741-7015-6-38

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