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Upregulation of CRABP1 in human neuroblastoma cells overproducing the Alzheimer-typical Aβ(42 )reduces their differentiation potential
BACKGROUND: Alzheimer's disease (AD) is characterized by neurodegeneration and changes in cellular processes, including neurogenesis. Proteolytic processing of the amyloid precursor protein (APP) plays a central role in AD. Owing to varying APP processing, several β-amyloid peptides (Aβ) are ge...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645429/ https://www.ncbi.nlm.nih.gov/pubmed/19087254 http://dx.doi.org/10.1186/1741-7015-6-38 |