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Lack of MD2 expression in human corneal epithelial cells is an underlying mechanism of lipopolysaccharide (LPS) unresponsiveness

In the present study we tested the responsiveness of human corneal epithelial cells (HCECs) and corneal fibroblasts to lipopolysaccharide (LPS), a TLR4 ligand. Purified P aeruginosa LPS was used to stimulate telomerase-immortalized HCECs (HUCL) and stromal fibroblast (THK) cell lines. Exposure of ce...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Kumar, Ashok, Wheater, Michelle, Yu, Fu-Shin X.
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645480/
https://www.ncbi.nlm.nih.gov/pubmed/18936773
http://dx.doi.org/10.1038/icb.2008.75