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A Temporal Threshold for Formaldehyde Crosslinking and Fixation
BACKGROUND: Formaldehyde crosslinking is in widespread use as a biological fixative for microscopy and molecular biology. An assumption behind its use is that most biologically meaningful interactions are preserved by crosslinking, but the minimum length of time required for an interaction to become...
Autores principales: | Schmiedeberg, Lars, Skene, Pete, Deaton, Aimée, Bird, Adrian |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645674/ https://www.ncbi.nlm.nih.gov/pubmed/19247482 http://dx.doi.org/10.1371/journal.pone.0004636 |
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