Normal Aging Modulates the Neurotoxicity of Mutant Huntingtin

Aging likely plays a role in neurodegenerative disorders. In Huntington's disease (HD), a disorder caused by an abnormal expansion of a polyglutamine tract in the protein huntingtin (Htt), the role of aging is unclear. For a given tract length, the probability of disease onset increases with ag...

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Detalles Bibliográficos
Autores principales: Diguet, Elsa, Petit, Fanny, Escartin, Carole, Cambon, Karine, Bizat, Nicolas, Dufour, Noëlle, Hantraye, Philippe, Déglon, Nicole, Brouillet, Emmanuel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645678/
https://www.ncbi.nlm.nih.gov/pubmed/19247483
http://dx.doi.org/10.1371/journal.pone.0004637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645678/
https://www.ncbi.nlm.nih.gov/pubmed/19247483
http://dx.doi.org/10.1371/journal.pone.0004637

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