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Chemotherapy Synergizes with Radioimmunotherapy Targeting La Autoantigen in Tumors

BACKGROUND: To date, inefficient delivery of therapeutic doses of radionuclides to solid tumors limits the clinical utility of radioimmunotherapy. We aim to test the therapeutic utility of Yttrium-90 ((90)Y)-radio-conjugates of a monoclonal antibody, which we showed previously to bind specifically t...

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Detalles Bibliográficos
Autores principales: Al-Ejeh, Fares, Darby, Jocelyn M., Brown, Michael P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645682/
https://www.ncbi.nlm.nih.gov/pubmed/19247485
http://dx.doi.org/10.1371/journal.pone.0004630