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Lipoic Acid Synthase (LASY): A Novel Role in Inflammation, Mitochondrial Function, and Insulin Resistance

OBJECTIVE—Lipoic acid synthase (LASY) is the enzyme that is involved in the endogenous synthesis of lipoic acid, a potent mitochondrial antioxidant. The aim of this study was to study the role of LASY in type 2 diabetes. RESEARCH DESIGN AND METHODS—We studied expression of LASY in animal models of t...

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Detalles Bibliográficos
Autores principales: Padmalayam, Indira, Hasham, Sumera, Saxena, Uday, Pillarisetti, Sivaram
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646058/
https://www.ncbi.nlm.nih.gov/pubmed/19074983
http://dx.doi.org/10.2337/db08-0473