Cargando…

Dact1, a Nutritionally Regulated Preadipocyte Gene, Controls Adipogenesis by Coordinating the Wnt/β-Catenin Signaling Network

OBJECTIVE—Wnt signaling inhibits adipogenesis, but its regulation, physiological relevance, and molecular effectors are poorly understood. Here, we identify the Wnt modulator Dapper1/Frodo1 (Dact1) as a new preadipocyte gene involved in the regulation of murine and human adipogenesis. RESEARCH DESIG...

Descripción completa

Detalles Bibliográficos
Autores principales: Lagathu, Claire, Christodoulides, Constantinos, Virtue, Sam, Cawthorn, William P., Franzin, Chiara, Kimber, Wendy A., Nora, Edoardo Dalla, Campbell, Mark, Medina-Gomez, Gema, Cheyette, Benjamin N.R., Vidal-Puig, Antonio J., Sethi, Jaswinder K.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646059/
https://www.ncbi.nlm.nih.gov/pubmed/19073771
http://dx.doi.org/10.2337/db08-1180